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Oxidative Stress
Brain-targeted ingredients keep your brain active and help it detox.

Free-radical induced damage may lead to brain aging

Aging is characterized by a progressive decline in the efficiency of physiological function and by increased susceptibility to disease. Currently, one of the most plausible and acceptable explanations for the mechanistic basis of aging is the "free radical theory of aging." This theory postulates that aging, and its related diseases, are the consequence of free radical-induced damage to all cells in the body and the inability to counterbalance these ill-effects with the body’s own anti-oxidant defenses. In layman's terms, this is commonly referred to as oxidative stress of the entire body — but the brain suffers the most. Because it's so active, the brain makes a lot of oxygen-toxic particles in a very small place, so oxygen builds up quickly. This causes extensive damage, which can’t be neutralized by the body’s own natural anti-oxidant defenses. The result is the brain and nerve cells cannot regenerate or produce energy, leading to impaired cognitive function.

Eating healthy foods provides the needed antioxidants to detoxify harmful oxidative particles. People who consume nutrient-poor foods are unable to negate the toxic effects of the oxygen particles. Antioxidant damage is seen in patients with dementia and Alzheimer’s disease, confirming a relationship between poor diet and impaired cognition. Moreover, people with higher blood levels of essential nutrients have lower risk of developing Alzheimer’s disease as they age.

Brain-targeted ingredients: acetyl-l-carnitine, alpha-lipoic acid, N-acetylcysteine, coenzyme Q10

Most people consume nutrient-poor foods for a long time, which leads to oxygen-related damage to the mitochondria, the energy-producing part of the brain. This damage adversely affects normal memory and problem-solving tasks. Patients with Alzheimer’s disease have oxygen-related damage to brain cells and lower energy production. In addition to consuming a nutrient-poor diet, a lifetime exposure to air pollution and stress from daily life place additional burdens on the brain.Humans need protection against oxidation during aging to avoid cognitive impairment. Even with a nutrient-dense diet rich in antioxidants, the human brain is still poorly equipped to squelch all of the oxygen particles. Safe bioactive compounds such as coenzyme Q10, alpha-lipoic acid, acetyl-l-carnitine, and N-acetyl cysteine offer additional protection against oxygen particle damage, thereby preserving healthy brain function with aging.

Humans need protection against oxidation during aging to avoid cognitive impairment. Even with a nutrient-dense diet rich in antioxidants, the human brain is still poorly equipped to squelch all of the oxygen particles. Safe bioactive compounds such as coenzyme Q10, alpha-lipoic acid, acetyl-l-carnitine, and N-acetyl cysteine offer additional protection against oxygen particle damage, thereby preserving healthy brain function with aging.



References

Shenk JC. Acetyl L-carnitine and alpha lipoic acid
Englehart MJ. Antioxidants
Ames BN. Antioxidants, triage theory
Assmann KE. Nutrient-dense diet with antioxidants 
Kidd PM. Co-Q10 and cognition
Shahrapour RB. N-acetyl cysteine and brain 
Holmay MJ. N-acetyl cysteine and brain
Pham-Huy LA Oxidative stress
Gemma C. Oxidative stress and the brain
Ames BN. Antioxidants, triage theory
Mohajeri MH. Nutrients and aging brain
Jacka FN. Nutrient-poor diet and brain atrophy
Berti V. Essential nutrients and prevent Alzheimer’s disease

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